Sequence:

MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT

Molecular weight:

Monomer, 17.7 kDa (155aa)

Recipe:

CTGrade GMP rhFLT-3 ligand was freeze-dried at 1 mg/ml in 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5, 0.2 μ m filtration

Protein purity:

≥ 97% determined by reduced and non reduced SDS-PAGE analysis

Endotoxins:

< 0.05 EU/μg

Biological activity:

ED50 is determined by dose-dependent proliferation of OCI-AML5 cells. ED50 is usually less than 5 ng/mL.

English description:

FLT-3 Ligand is a growth factor that regulates proliferation of early hematopoietic cells. FLT-3 Ligand binds to cells expressing the tyrosine kinase receptor FLT-3.