12 months
Sequence:
MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQENPCGP CSERRKHLFV QDPQTCKCSC KNTDSRCKAR QLELNERTCR CDKPRR
Molecular weight:
Dimer,19.3/38.6 kDa (166/332 aa)
Recipe:
Freeze dry from a 0.2 μ m filtered solution containing 0.1% trifluoroacetic acid (TFA)
Protein purity:
≥ 95% determined by reduced and non reduced SDS-PAGE analysis
Endotoxins:
≤ 0.1 EU/μg
Biological activity:
HUVEC proliferation ≤ 10 ng/mL
English description:
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.