Sequence:

MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS

Molecular weight:

Monomer, 15.1 kDa (130 aa)

Recipe:

Freeze dry from a 0.2 μm filtered solution containing 0.1% trifluoroacetic acid (TFA)

Protein purity:

≥ 95% determined by reduced and non reduced SDS-PAGE analysis

Endotoxins:

≤ 0.1 EU/μg

Biological activity:

TF-1 cell proliferation ED50 ≤ 0.25 ng/mL

English description:

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells.