Sequence:

MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM

Molecular weight:

Monomer, 20.9 kDa (185aa)

Recipe:

CTGrade GMP rhIL-6 was freeze-dried at a concentration of 1 mg/ml in 10 mM sodium phosphate (pH 7.5, 0.2 μm)

Protein purity:

≥ 97% determined by reduced and non reduced SDS-PAGE analysis

Endotoxins:

< 0.05 EU/μg

Biological activity:

ED50 is determined by dose-dependent proliferation of B9 cells. ED50 is usually less than 0.025 ng/mL

English description:

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells