Sequence:

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

Molecular weight:

Monomer, 14.6 kDa (128 aa)

Recipe:

Freeze dry from a 0.2 μ m filtered solution containing 10 mM sodium phosphate (pH 7.5)

Protein purity:

≥ 95% determined by reduced and non reduced SDS-PAGE analysis

Endotoxins:

≤ 0.1 EU/µg

Biological activity:

TF-1 cell proliferation ≤ 0.2 ng/mL

English description:

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.