Sequence:

SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNELPNRTSG LLETNFTASA RTTGSGLLKW QQGFRAKIPG LLNQTSRSLD QIPGYLNRIH ELLNGTRGLF PGPSRRTLGA PDISSGTSDT GSLPPNLQPG YSPSPTHPPT GQYTLFPLPP TLPTPVVQLH PLLPDPSAPT PTPTSPLLNT SYTHSQNLSQ EGHHHHHH

Molecular weight:

Monomer, 36.3 kDa (338 aa)

Recipe:

Freeze dry from a 0.2 μm filtered solution containing 5 mM sodium phosphate and 2 mM L-arginine (pH 7.5)

Protein purity:

≥ 90% determined by reduced and non reduced SDS-PAGE analysis

Endotoxins:

≤ 0.1 EU/μg

Biological activity:

MO7e cell proliferation ≤ 15 ng/mL

English description:

Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets.